Vitamin D derivatives modified in the 20-position and pharmaceutical compositions thereof

US5700791A · kind A · utility

Assignee

• SCHERING CORPORATION · US

Inventors

• Andreas Steinmeyer · Berlin, DE
• Gunter Neef · Berlin, DE
• Gerald Kirsch · Berlin, DE
• Katica Schwarz · Berlin, DE
• Ruth Thieroff-Ekerdt · Concord, US
• Herbert Wiesinger · Berlin, DE
• Martin Haberey · Berlin, DE

Key dates

• Filing date: Jun 14, 1996
• Grant date: Dec 23, 1997
• Expiry date: Jun 14, 2016

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07F7/1804
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

The invention relates to vitamin D derivatives, modified in 20-position, of general formula I ##STR1## in which X, Y, Z, R.sub.1, R.sub.2 as well as R.sub.3 have the meaning indicated in the description, process for their production and their use as agents for treatment of hyperproliferative diseases of the skin.