Endothelin receptor antagonists

US5700807A · kind A · utility

Assignee

• Merck Patent GmbH · DE

Inventors

• Mathias Osswald · Zwingenberg, DE
• Dieter Dorsch · Ober-Ramstadt, DE
• Werner Mederski · Zwingenberg, DE
• Claudia Wilm · Darmstadt, DE
• Claus J. Schmitges · Groß-Umstadt, DE
• Maria Christadler · Darmstadt, DE

Key dates

• Filing date: Jul 26, 1996
• Grant date: Dec 23, 1997
• Expiry date: Jul 26, 2016

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D495/04
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Novel compounds of the formula ##STR1## in which --Y--Z--, R.sup.1 R.sup.2, R.sup.3, R.sup.4, R.sup.5 and X have the meaning indicated and their salts show endothelin receptor-antagonistic properties.