4-substituted azetidinones as precursors to 2-substituted-3-carboxy carbapenem antibiotics and a method of producing them
US5700930A · kind A · utility
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1Claims
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Key dates
| Filing date | Apr 12, 1995 |
| Grant date | Dec 23, 1997 |
| Priority date | — |
| Expiry date | Apr 12, 2015 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07F9/568
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
New 4-substituted azetidinones having the formulae I and II: ##STR1## wherein X is oxygen, sulfur or a moiety of the formula NR.sup.6 where R.sup.1, R.sup.2, R.sup.3, R.sup.4, R.sup.5 and R.sup.6 are defined hereafter, which are intermediates for the preparation of carbapenem and carbacephem antibacterials and processes for producing such antibacterials through the utilization of an acid mediated ring closure reaction.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.