Patent · US Expired

Mutagenesis methods and compositions

US5702931A · kind A · utility

11Cited by
2References
12Claims
0Family size

Assignee

Inventors

Key dates

Filing dateDec 28, 1993
Grant dateDec 30, 1997
Priority date
Expiry dateDec 28, 2013

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC12N2830/85
  • WIPO fieldBiotechnology
  • WIPO sectorChemistry

Abstract

Methods and reagents for oligonucleotide-directed mutagenesis of a target nucleic acid are provided. In these methods a mutagenic oligonucleotide introduces a desired mutation at one site and, at a second site, introduces or eliminates a restriction site, allowing one to screen for the desired mutation by restriction analysis. Also provided are vectors and kits for performing such mutagenesis methods.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.