Saccular collagen and compositions and methods for making and using the same

US5702948A · kind A · utility

Assignee

• The Trustees of the University of Pennsylvania · US

Inventors

• Mark I. Greene · Levittown, US
• James G. Davis · Rochester, US

Key dates

• Filing date: Feb 2, 1995
• Grant date: Dec 30, 1997
• Expiry date: Feb 2, 2015

Classification

• Technology area (CPC G): Physics
• CPC primary: G03C1/047
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

A substantially purified saccular collagen protein and compositions, including pharmaceutical compositions, that comprise the saccular collagen protein are disclosed. Methods of using the saccular collagen which comprise injecting the saccular collagen into the tissue of an individual are disclosed. Antibodies which bind to the saccular collagen protein, nucleic acid molecules which encode the saccular collagen protein, and oligonucleotides which are identical or complementary to at least a portion of the sequence that encodes the saccular collagen proteins are disclosed. Recombinant expression vector that comprise nucleic acid molecules that encode the saccular collagen protein and host cells, including the cells of transgenic animals, which comprise the recombinant expression vectors are disclosed.