Urea derivatives, their preparation and use

US5703050A · kind A · utility

Assignee

• Hoechst GmbH · DE

Inventors

• Otmar Klingler · Rodgau, DE
• Gerhard Zoller · Blankenloch, DE
• Bernd Jablonka · Bad Soden, DE
• Melitta Just · Langen, DE
• Gerhard Breipohl · Scheinfeld, DE
• Jochen Knolle · Kriftel, DE
• Wolfgang Konig · Hofheim, DE
• Hans Ulrich Stilz · Frankfurt am Main, DE

Key dates

• Filing date: Jan 17, 1996
• Grant date: Dec 30, 1997
• Expiry date: Jan 17, 2016

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61K38/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Urea derivates are disclosed having the formula (I). ##STR1## in which A, B, W, Z, R, R.sup.1, R.sup.2, R.sup.3 and r have the meaning given in the description, as well as a process for preparing the same and their use as inhibitors of thrombocyte aggregation, carcinom cell metastasis and osteoclast binding to bone surface.