Patent · US Expired

Process and solvate of 2-methyl-thieno-benzodiazepine

US5703232A · kind A · utility

20Cited by
5References
8Claims
0Family size

Assignee

Inventors

Key dates

Filing dateJan 16, 1996
Grant dateDec 30, 1997
Priority date
Expiry dateJan 16, 2016

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D495/04
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

The invention provides lower alcohol solvates of 2-methyl-4-(4-methyl-1-piperazinyl)-10H-thieno2,3-b!1,5!benzodiazepine (olanzapine) and a process for making such lower alcohol solvates of olanzapine. The invention provides a method for using such solvates of olanzapine to prepare substantially pure anhydrous Form I 2-methyl-thieno-benzodiazepine.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.