Sustained delivery of active compounds from tubules, with rational control
US5705191A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Aug 18, 1995 |
| Grant date | Jan 6, 1998 |
| Priority date | — |
| Expiry date | Aug 18, 2015 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K9/1274
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention is a method for releasing an active agent into a use nvironment, by disposing this active agent within the lumen of a population of tubules, and disposing the tubules into a use environment, either directly or in some matrix such as a paint in contact with the use environment. The tubules have a preselected release profile to provide a preselected release rate curve. The preselected release profile may be achieved by controlling the length or length distribution of the tubules, or by placing degradable endcaps over some or all of the tubules in the population, or by combinations of these methods. The invention is also a population of tubules having a preselected release profile to provide a preselected release rate curve.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.