Oligonucleotides that inhibit production of .alpha.-tumor necrosis factor
US5705389A · kind A · utility
22Cited by
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9Claims
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Assignee
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Key dates
| Filing date | Nov 18, 1994 |
| Grant date | Jan 6, 1998 |
| Priority date | — |
| Expiry date | Nov 18, 2014 |
Classification
- Technology area (CPC H)Electricity
- CPC primaryH02K2203/03
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
A sequence of anti-direction, anti-messenger RNA oligonucleotides of .alpha.-TNF characterized in that it possesses the structure of the formula ##STR1## wherein X is hydrogen, or a sequence of 1 to 17 oligonucleotides in free form, in alkylated form, in sulfurated form or in the form of a poly L-lysine derivative useful for stopping the production of .alpha.-TNF.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.