Sulfamate derivatives of 1,3,5(10)-estratriene derivatives, methods for their production and pharmaceuticals containing these compounds

US5705495A · kind A · utility

Assignee

• Jenapharm GmbH & Co. KG · DE

Inventors

• Sigfrid Schwarz · Jena, DE
• Walter Elger · Berlin, DE
• Gudrun Reddersen · Jena, DE
• Birgitt Schneider · Jena, DE
• Ina Thieme · Graitschen, DE
• Margit Richter · Jena, DE

Key dates

• Filing date: Oct 18, 1996
• Grant date: Jan 6, 1998
• Expiry date: Oct 18, 2016

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07J41/0072
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

The invention relates to new sulfamate derivatives of 1,3,5(10)-estratriene derivatives of the general formula I ##STR1## wherein the 3-sulfamate moiety is acylated, sulfonated or amidosulfonated. Furthermore, methods for the production of the compound and pharmaceutical preparations containing this compound are described. The compounds according to the invention have an estrogenic effect.