Anti-tumor compounds, pharmaceutical compositions, methods for preparation thereof and for treatment
US5705508A · kind A · utility
30Cited by
7References
30Claims
0Family size
Assignees
Inventors
Key dates
| Filing date | Oct 13, 1995 |
| Grant date | Jan 6, 1998 |
| Priority date | — |
| Expiry date | Oct 13, 2015 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY02P20/55
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The present invention is directed to novel taxanes useful as chemotherapeutic agents or their precursors. Processes for preparing the novel taxanes include coupling reactions, in the presence of a base, of baccatin of formula (III) or (IV) ##STR1## with .beta.-lactams of formula (V). ##STR2## The invention also provides pharmaceutical compositions including the novel taxanes and methods for treatment of certain cancers with these new compounds.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.