Patent · US Expired

Nucleic acid probes and methods

US5707813A · kind A · utility

26Cited by
2References
18Claims
0Family size

Assignee

Inventors

Key dates

Filing dateSep 6, 1996
Grant dateJan 13, 1998
Priority date
Expiry dateSep 6, 2016

Classification

  • Technology area (CPC G)Physics
  • CPC primaryG01N2333/19
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

The present invention is directed to compositions comprising an oligonucleotide linked to a detectably labeled marker component comprising a fluorophore moiety which comprises a substantially planar, multidentate macrocyclic ligand coordinated to a central atom capable of coordinating with two axial ligands and two polyoxyhydrocarbyl moieties which are attached as axial ligands to the central atom. The present invention is also directed to nucleic acid hybridization and amplification methods employing such compositions.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.