Process for the preparation of human factor VIII and analogs of factor VIII
US5707832A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Feb 7, 1995 |
| Grant date | Jan 13, 1998 |
| Priority date | — |
| Expiry date | Feb 7, 2015 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K38/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to a process for the preparation of factor VIII or an analog of factor VIII by culture, in a culture medium, of cells which produce said factor VIII or analog of factor VIII and the separation of factor VIII or its analog, wherein the culture medium contains at least one derivative of a polycationic and/or polyanionic polymer. It also relates to factor VIII or analog of factor VIII and to the complex of factor VIII or analog of factor VIII with a derivative of a polycationic and/or polyanionic polymer obtained by using this process.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.