Method of producing (R)-tertiary leucine

US5707837A · kind A · utility

Assignee

• Degussa AG · DE

Inventors

• Karlheinz Drauz · Alzenau, DE
• Andreas Bommarius · Frankfurt, DE
• Matthias Kottenhahn · Alzenau, DE

Key dates

• Filing date: Aug 9, 1996
• Grant date: Jan 13, 1998
• Expiry date: Aug 9, 2016

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C12P41/009
• WIPO field: Biotechnology
• WIPO sector: Chemistry

Abstract

A method is disclosed by which N-carbamoyl-(R)-tert.-leucine is obtained from tert-butyl hydantoin by means of an (R)-specific hydantoinase, in which N-carbamoyl-(R)-tert.-leucine is converted by reaction with nitrite or an (R)-carbamoylase to (R)-tert-leucine.