Inhibition of attachment of H.influenzae to human cells
US5707968A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Oct 23, 1996 |
| Grant date | Jan 13, 1998 |
| Priority date | — |
| Expiry date | Oct 23, 2016 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S530/832
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The attachment of H. influenzae to human cells, such as oropharyngeal cells, may be inhibited by native human .beta.-casein, a recombinant form of human .beta.-casein, and hydrolysates of both. The human .beta.-casein or hydrolysate may be contained in a liquid enteral nutritional product such as an infant formula. The enteral nutritional product may be used, for example, in the prevention and treatment of otitis media in infants. The human .beta.-casein or hydrolysate may also be administered as a throat spray or nasally using drops or a spray.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.