Intrapulmonary delivery of aerosolized formulations
US5709202A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | May 21, 1993 |
| Grant date | Jan 20, 1998 |
| Priority date | — |
| Expiry date | May 21, 2013 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61M2230/40
- WIPO fieldMedical technology
- WIPO sectorInstruments
Abstract
Liquid, flowable formulations including aqueous formulations of a pharmaceutically active drug are packaged in individual dosage unit containers which containers are interconnected to form a cellular array designed to be integrated into a dispensing device capable of individually opening dosage unit containers and aerosolizing the contents through a nozzle for delivery to a patient. The cellular array is comprised of a plurality of containers with each container having an opening(s) thereon from which a drug-containing formulation may be aerosolized. The dispensing device is a hand-held, self-contained, portable device comprised of a means for removing covers from the containers and automatically dispensing the formulation from individual containers, preferably in response to a signal obtained as a result of measuring the inspiratory flow of a patient. The cellular array is loaded into the dispensing device to form a system which can be used in a method of delivering drugs to a patient via the intrapulmonary route. In a preferred embodiment each container includes an opening covered by a membrane having a plurality of pores therein wherein the pores have a diameter of about 0.5 mic…
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.