Patent · US Expired

Process for conditioning substances

US5709884A · kind A · utility

54Cited by
4References
22Claims
0Family size

Assignee

Inventors

Key dates

Filing dateJan 30, 1995
Grant dateJan 20, 1998
Priority date
Expiry dateJan 30, 2015

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07C2601/14
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

The present invention relates to a process for providing a stable crystallinic form to a fine-grained substance or a substance mixture, which can be produced, stored and used while maintaining the aerodynamic properties required for inhalation of such a substance or a substance mixture, by PA1 a) in case of a substance mixture, preparing a homogenous mixture of the substances; PA1 b) micronizing, direct precipitating or diminishing by any conventional method the substance or substance mixture into a particle size required for inhalation, the particle size being less than 10 .mu.m; PA1 c) optionally preparing a homogenous mixture of the desired substances when each substance has been introduced from stage b) as separate fine-grained particles; PA1 d) conditioning said substance or substance mixture by treatment with a water containing vapor phase in a controlled fashion; and PA1 e) drying.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.