Patent · US Expired

Human potassium channel 1 and 2 proteins

US5710019A · kind A · utility

5Cited by
1References
14Claims
0Family size

Assignee

Inventors

Key dates

Filing dateJun 5, 1995
Grant dateJan 20, 1998
Priority date
Expiry dateJun 5, 2015

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC12N2799/026
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

Disclosed are human K.sub.+ channel polypeptides and DNA (RNA) encoding such K.sub.+ channel polypeptides. Also provided is a procedure for producing such polypeptides by recombinant techniques. Agonists for such K.sub.+ channel polypeptides are also disclosed. Such agonists may be used to treat epilepsy, stroke, hypertension, asthma, Parkinson's disease, schizophrenia, anxiety, depression and neurodegeneration. Also disclosed are antagonists against such polypeptides which may be used to treat AIDS, SLE, diabetes, multiple sclerosis and cancer. Also disclosed are diagnostic assays for detecting mutations in the polynucleotide sequences of the present invention.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.