Human elastase IV
US5710035A · kind A · utility
9Cited by
2References
36Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jul 5, 1994 |
| Grant date | Jan 20, 1998 |
| Priority date | — |
| Expiry date | Jul 5, 2014 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K38/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Human elastase IV polypeptides and DNA (RNA) encoding such polypeptides and a procedure for producing such polypeptide by recombinant techniques and utilizing such polypeptide for therapeutic purposes, for example, restoration of elasticity of arterial walls, improvement of serum lipid abnormality and improvement of serum lipoprotein metabolism are disclosed. Also disclosed are antagonist/inhibitors against such polypeptides and their use in treating inflammation, arthritis, e.g. rheumatoid arthritis and osteoarthritis, septic shock, pancreatitis and limiting tissue damage in ulceration.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.