Synergistic combinations of active substance for the cosmetic or dermatological care of the skin, hair & nails

US5710177A · kind A · utility

Assignee

• BEIERSDORF AG · DE

Inventors

• Gerhard Sauermann · Wiemersdorf, DE
• Uwe Schonrock · Norderstedt, DE
• Volker Schreiner · Hamburg, DE
• Franz Stab · Echem, DE

Key dates

• Filing date: Aug 11, 1995
• Grant date: Jan 20, 1998
• Expiry date: Aug 11, 2015

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61Q19/007
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Cosmetic and/or dermatological active compound combinations comprising PA1 a) an active amount of biotin and/or biotin esters, PA1 b) an active amount of one or more .alpha.-hydroxycarboxylic acids of the formula EQU R'(R")(OH)C COOH and/or an active amount of one or more .alpha.-ketocarboxylic acids of the formula EQU R'C(O) COOH or their physiologically acceptable salts or esters wherein R' and R" represent H-; branched or unbranched C.sub.1-25 -alkyl- or C.sub.1-25 -alkyl-substituted by one or more carboxyl groups and/or hydroxyl groups and/or a aldehyde groups and/or oxo groups (keto groups); phenyl- or phenyl substituted by one or more carboxyl groups and/or hydroxyl groups and/or branched and/or unbranched C.sub.1-25 -alkyl groups; or wherein the .alpha.-carbon atom of the .alpha.-hydroxycarboxylic acid, together with R' and R", forms a cycloalkyl group having 3 to 7 ring atoms or the cycloalkyl substituted by one or more carboxyl groups and/or hydroxyl groups and/or oxo groups (keto groups) and/or branched and/or unbranched C.sub.1-25 -alkyl groups; and PA1 c) an active amount of one or more antioxidants.