Patent · US Expired

Ophthalmic composition

US5710182A · kind A · utility

19Cited by
0References
12Claims
0Family size

Assignee

Inventors

Key dates

Filing dateApr 2, 1996
Grant dateJan 20, 1998
Priority date
Expiry dateApr 2, 2016

Classification

  • Technology area (CPC A)Human Necessities
  • CPC primaryA61P27/02
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

The present invention is directed to an ophthalmic composition in the form of a topical aqueous solution consisting essentially of PA0 an ophthalmologically active agent, PA0 an ion sensitive, hydrophilic polymer in an amount a of 0.004 to 1.5% by weight, PA0 at least one salt selected from the group of inor ganic salts and buffers in a total amount of from 0.01 to 2.0% by weight, PA0 a wetting agent in an amount of 0 to 3.0% by weight, PA0 a preservative in an amount of 0 to 0.02% by weight, PA0 water, and optionally PA0 a pH regulating agent in an amount sufficient to give a pH of 4.0 to 8.0 to the composition, the ratio between salt and polymer components being such that the solution exhibits a viscosity of less than 1000 mPas. The composition contains a sufficient amount of polymer to provide for a controlled absorption of the drug into the eye, its viscosity having been reduced to provide for better handling characteristics.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.