Patent · US Expired

Optical solid-phase biosensor based on polyionic layers labelled with fluorescent dyes

US5711915A · kind A · utility

92Cited by

2References

8Claims

0Family size

Assignee

BAYER HEALTHCARE LLC · DE

Inventors

Hans-Ulrich Siegmund · Cologne, DE
Ludger Heiliger · Leverkusen, DE
Boudewijn van Lent · Bensberg, DE
Arno Becker

Key dates

Filing date	Oct 24, 1995
Grant date	Jan 27, 1998
Priority date	—
Expiry date	Oct 24, 2015

Classification

Technology area (CPC Y)Emerging Cross-Sectional Technologies
CPC primaryY10S435/808
WIPO fieldMeasurement
WIPO sectorInstruments

Abstract

The present invention relates to an optical solid-phase biosensor for the detection of molecules which can be labelled with a fluorescent dye for the identification of substances in solution, for which there exists a biomolecule (receptor) which specifically recognises these and is chemically bonded to the uppermost layer of one or more layers of polyions on the surface of the sensor, by measurement of the Forster transfer between another dye molecule which is bonded in one of the uppermost layers of the sensor, and the said dye molecule.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.