Interferon polymer conjugates
US5711944A · kind A · utility
163Cited by
16References
28Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Nov 10, 1994 |
| Grant date | Jan 27, 1998 |
| Priority date | — |
| Expiry date | Nov 10, 2014 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K38/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A process is disclosed for preparing long-acting alpha interferon-containing compositions. Alpha interferon is contacted with a relatively small molar excess of a substantially non-antigenic polymer in the presence of a surfactant to preserve bioactivity. Isolation of the desired conjugate species having optimal activity is also disclosed.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.