Transdermal therapeutic system for application of pharmaceuticals onto the skin

US5711962A · kind A · utility

Assignee

• Rotta Research Laboratorium S.p.A. · IT

Inventors

• Gunter Cordes · Leichlingen, DE
• Lucio Claudio Rovati · Monza, IT

Key dates

• Filing date: Mar 27, 1996
• Grant date: Jan 27, 1998
• Expiry date: Mar 27, 2016

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61K31/57
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Transdermal therapeutic systems containing as active ingredients oestradiol and norethisterone acetate have added thereto octyldodecanol to reduce or avert crystal formation after storage. The use of octyldodecanol thus makes it possible to produce a storage-stable system with the active ingredients oestradiol and norethisterone acetate with a high thermodynamic activity.