Mixture having antitumor activities
US5712123A · kind A · utility
0Cited by
3References
6Claims
0Family size
Assignee
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Key dates
| Filing date | Oct 6, 1995 |
| Grant date | Jan 27, 1998 |
| Priority date | — |
| Expiry date | Oct 6, 2015 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S435/863
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A purified hot-water extract from Mycobacterium bovis (BCG vaccine) has been found to have significant antitumor activity against a mouse bladder tumor model and a murine sarcoma in vivo, but not in vitro. The material, termed PS1A1, has an approximate molecular weight of between 60 and 90 kDa, is freely soluble in water, but has low solubility in acetone or ethanol, and is remarkably heat-stable.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.