Chemical compounds
US5714148A · kind A · utility
4Cited by
1References
21Claims
0Family size
Assignees
Inventors
Key dates
| Filing date | Sep 30, 1996 |
| Grant date | Feb 3, 1998 |
| Priority date | — |
| Expiry date | Sep 30, 2016 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07C311/51
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Prodrugs, of generic formula I, are disclosed for use in antibody directed enzyme prodrug therapy (ADEPT). The prodrugs are substrates for carboxypeptidase G2 (CPG2) and yield more active cytotoxic drugs than known products of CPG2 catalysed reactions.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.