Patent · US Expired

Saliva assay method and device

US5714341A · kind A · utility

100Cited by
10References
20Claims
0Family size

Assignee

Inventors

Key dates

Filing dateMar 30, 1994
Grant dateFeb 3, 1998
Priority date
Expiry dateMar 30, 2014

Classification

  • Technology area (CPC Y)Emerging Cross-Sectional Technologies
  • CPC primaryY10S435/81
  • WIPO fieldMeasurement
  • WIPO sectorInstruments

Abstract

An improved method for determining the presence of an analyte in an oral fluid sample. A portion of the sample is mixed or contacted with a chromogenic substrate effective to produce a colored product upon reaction with .alpha.-amylase present in the sample. After a selected reaction time, the reaction mixture is inspected to determine the level of such colored product produced. Production of a level of colored product above a selected threshold within the reaction time indicates that an effective volume of undiluted oral fluid sample has been collected which is sufficient to allow detection of the analyte. A device for use in the method is also disclosed.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.