Antibacterial and antimalarial hybrid peptides
US5714467A · kind A · utility
13Cited by
0References
22Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Mar 26, 1993 |
| Grant date | Feb 3, 1998 |
| Priority date | — |
| Expiry date | Mar 26, 2013 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2319/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention relates to antibacterial and antimalarial peptides which are hybrids peptides which a of naturally occurring peptides such as cecropins, attacins, magainins, sarcotoxin, sapecin, bactenecins, alamethidicins, defensins and PGLa, and toxins such as streptolysins, melittin, barbatolysin, paradaxins and delta hemolysin. The hybrid peptides of the present invention are easily synthesized and have reduced toxicity. Also included in the invention are pharmaceutical compositions containing such hybrid peptides, and methods of treating patients infected with an organism against which these peptides are active.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.