Patent · US Expired

Pharmaceutical composition containing heparin, heparin fragments or their derivatives in combination with glycerol esters

US5714477A · kind A · utility

73Cited by
4References
20Claims
0Family size

Assignee

Inventor

Key dates

Filing dateDec 4, 1995
Grant dateFeb 3, 1998
Priority date
Expiry dateDec 4, 2015

Classification

  • Technology area (CPC A)Human Necessities
  • CPC primaryA61P7/02
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

The present invention relates to pharmaceutical compositions containing heparin or heparin fragments or their derivatives in combination with one or more glycerol esters of at least one fatty acid as single absorption enhancer. The compositions are useful for oral administration, for administration through mucous membranes or for transdermal administration. The compositions will when necessary contain further physiologically acceptable additives, such as diluents and/or carriers, suitable for the adaptation to oral, buccal, rectal, sublingual, nasal, subcutaneous or transdermal administration. The composition according to the invention provide excellent absorption and bioavailability without employing additional enhancers or promoters.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.