3-amino-2-oxo-1-piperidineacetic derivatives containing an arginine mimic as enzyme inhibitors
US5714499A · kind A · utility
17Cited by
0References
32Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jun 17, 1994 |
| Grant date | Feb 3, 1998 |
| Priority date | — |
| Expiry date | Jun 17, 2014 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K38/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention discloses peptide aldehydes which are potent and specific inhibitors of thrombin, their pharmaceutically acceptable salts, pharmaceutically acceptable compositions thereof, and methods of using them as therapeutic agents for disease states in mammals characterized by abnormal thrombosis.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.