Conjugates possessing ortho ligating functionality
US5714631A · kind A · utility
19Cited by
13References
4Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Feb 6, 1996 |
| Grant date | Feb 3, 1998 |
| Priority date | — |
| Expiry date | Feb 6, 2016 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K2123/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A group of functionalized amine chelants having ortho ligating functionality that form complexes with rare-earth type metal ions are disclosed. The complexes can be covalently attached to an antibody or antibody fragment and used for therapeutic and/or diagnostic purposes. In addition certain of the chelant-radionuclide complexes can be effectively employed in compositions useful as therapeutic and/or diagnostic agents for calcific tumors and/or relief of bone pain.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.