Resolution of immixtures of stereoisomeric alcohols
US5714642A · kind A · utility
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Key dates
| Filing date | Sep 5, 1995 |
| Grant date | Feb 3, 1998 |
| Priority date | — |
| Expiry date | Sep 5, 2015 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12P7/02
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Immixture of stereoisomeric alcohols is resolved by selectively enzymatically acylating one of the stereoisomers thereof, in the presence of a catalytically effective amount of a hydrolase, for example a lipase, esterase or acylase, in a biphasic hydroorganic reaction medium, and thence separating the alcohol stereoisomer from the ester stereoisomer thus formed.
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