Calibration of segmental blood volume changes in arteries and veins during detection of atherosclerosis
US5715828A · kind A · utility
Inventors
Key dates
| Filing date | Mar 1, 1996 |
| Grant date | Feb 10, 1998 |
| Priority date | — |
| Expiry date | Mar 1, 2016 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61B2560/0223
- WIPO fieldMedical technology
- WIPO sectorInstruments
Abstract
The method of calibrating the volume plethysmograph designed to detect atherosclerosis includes selecting discrete levels of cuff pressure and placing the artery under study at those discrete levels of induced pressure with a closed pneumatic cuff system, substantially continually sensing cuff pressures at each discrete level and thereby sensing blood volume change through the artery, electronically determining when a certain number of representative blood volume change signals are substantially equivalent, changing the volume in the closed pneumatic system at each discrete cuff pressure by a predetermined volumetric amount after determining substantial equivalency, electronically generating a calibration signal or factor at each discrete cuff pressure based upon changed blood volume change signal and, correcting the blood volume change representative signal based upon the calibration signal or factor at each discrete level of pressure. The calibration device includes, in one embodiment, a controllable pneumatic pump, a pressure sensor, a computerized device for determining when a representative number of blood volume change signals (based on the pressure sensor signals) are substa…
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.