Preparation and use of novel cyclodextrin-based dispersible colloidal systems in the form of nanospheres
US5718905A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Mar 8, 1995 |
| Grant date | Feb 17, 1998 |
| Priority date | — |
| Expiry date | Mar 8, 2015 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10T428/2989
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A nanoparticulate system prepared by: 1) preparing a liquid phase essentially consisting of a solution of cyclodextrin modified by acyl groups in an organic solvent or solvent mixture, an active molecule being optionally added thereto; 2) preparing a second liquid phase essentially consisting of water or an aqueous mixture optionally containing one or more surfactants, and optionally having an active molecule added thereto; and 3) gently stirring one of the liquid phases resulting from 1) or 2) into the other in order to obtain, almost instantaneously, a colloidal solution of modified cyclodextrin nanospheres. If required, all or part of the solvent and all or part of the water may be removed. The system may be used as a carrier for pharmaceuticals, cosmetics, chemicals, etc.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.