Labeled complex and method of analysis therewith
US5719027A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Feb 22, 1996 |
| Grant date | Feb 17, 1998 |
| Priority date | — |
| Expiry date | Feb 22, 2016 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10T436/24
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
A labeled complex formed by combining a labeling agent with a biological substance, where the labeling agent is a trinucleus dye represented by the general formula (I)' or (II)': EQU ring(Xa)-La-ring(Xb)-Lb-ring(Xc) (I)' EQU ring(Xa)-La-ring(Xb)-Lb-ring(Xc)!.sup..sym. Y.sup..crclbar.(II)' where the ring(Xa), ring(Xb), and ring(Xc), which mean rings having Xa, Xb, or Xc respectively, are independently a heterocyclic ring having one to three heteroatoms of oxygen, sulfur, nitrogen, or selenium, the heterocyclic ring being unsubstituted or substituted by any of a substituted or unsubstituted alkyl group, a substituted or unsubstituted aryl group, and a substituted or unsubstituted aralkyl group; La and Lb are independently a methine chain composed of one to six substituted or unsubstituted methine linkage, and one of La and Lb may be omitted to link directly the heterocyclic rings; and Y.sup..crclbar. represents an anion. A method of analysis, comprises combining any of the labeled complex with a target substance to be detected, and detecting the target substance optically.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.