Cellulose binding domain fusion proteins

US5719044A · kind A · utility

Assignees

• YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD. · IL
• The Regents of the University of California · US

Inventors

• Oded Shoseyov · Karmei Yosef, IL
• Itai Shpiegl · Rehovot, IL
• Marc Goldstein · Davis, US
• Roy H. Doi · Davis, US

Key dates

• Filing date: Jun 2, 1995
• Grant date: Feb 17, 1998
• Expiry date: Jun 2, 2015

Classification

• Technology area (CPC Y): Emerging Cross-Sectional Technologies
• CPC primary: Y10S530/861
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

A cellulose binding domain (CBD) having a high affinity for crystalline cellulose and chitin is disclosed, along with methods for the molecular cloning and recombinant production thereof. Fusion products comprising the CBD and a second protein are likewise described. A wide range of applications are contemplated for both the CBD and the fusion products, including drug delivery, affinity separations, and diagnostic techniques.