2'-protected 3'-dimethylamine, 9-etheroxime erythromycin A derivatives
US5719272A · kind A · utility
24Cited by
2References
13Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Apr 2, 1996 |
| Grant date | Feb 17, 1998 |
| Priority date | — |
| Expiry date | Apr 2, 2016 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY02P20/55
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
A process of preparing a 6-O-methyl erythromycin A derivative using a 2'-protected, 9-etheroxime erythromycin A intermediate is provided. A preferred protecting group for the 2'-position is acetyl. 2'-protected, 9-etheroxime erythromycin A derivatives are also provided. Also disclosed is a method for inhibiting quaternary salt formation at the 3' amine without the need for 3'N-protecting groups.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.