Particle analyzer classifying particles of various biological types using a correlation of measurements
US5719666A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Nov 14, 1995 |
| Grant date | Feb 17, 1998 |
| Priority date | — |
| Expiry date | Nov 14, 2015 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2015/1019
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
A particle analyzer includes a flow cell including first and second cells for containing an electrolyte with various types of biological particles floating therein. The first and second cells are connected to each other by a pore to allow the particles to flow from the first cell to the second cell through the pore. A first and a second electrode are provided in the electrolyte in the first and second cells respectively. A first detector detects an electric resistance between the first and second electrodes which changes according as the particle passes through the pore to generate an electric resistance signal representative of the electric resistance. A light source emits a beam of light to the flowing particle and a second detector detects scattered light from the particle receiving the beam of light to generate a scattered light signal representative of an intensity of the scattered light. A clock device clocks a period of time during which the scattered light signal is generated. An analyzer classifies the particle as a particular type of biological particle based on a correlation between the electric resistance signal and the clocked period of time.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.