Peptides, active as inhibitors of platelet aggregation
US5721213A · kind A · utility
5Cited by
1References
27Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jan 30, 1996 |
| Grant date | Feb 24, 1998 |
| Priority date | — |
| Expiry date | Jan 30, 2016 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K14/745
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention provides compounds and salts thereof, that are represented by the formula: EQU Pro-Ser-A-B-Asp-C-D wherein A is an amino acid which does not contain a guanidino group as a side chain, B is a amino acid, C is a hydrophobic amino acid and D is a hydroxy group or an amino acid. The compounds of the invention have excellent platelet aggregation inhibiting and blood coagulation inhibiting activities. Also provided are reagents, pharmaceutical compositions and methods for inhibiting platelet aggregation and blood coagulation.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.