Substituted benzamides and radioligand analogs and methods of use
US5723103A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Dec 9, 1994 |
| Grant date | Mar 3, 1998 |
| Priority date | — |
| Expiry date | Dec 9, 2014 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K2123/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
This invention provides compounds of the formula I ##STR1## wherein, R.sup.1, R.sup.2, and R.sup.3 are independently a first halogen atom,! fluorine, chlorine, bromine, iodine, alkyl, alkenyl, alkynyl, alkoxy, alkenoxy, or alkynoxy, wherein R.sup.2 and R.sup.3 can also independently be H, wherein at least one of R.sup.1, R.sup.2, and R.sup.3 is a second halogen atom! fluorine, bromine, iodine or is substituted with a second halogen atom,! fluorine, bromine or iodine and R.sup.4 is H or lower alkyl. The invention also provides precursors of formula I, radioactive analogs of formula I, and methods of using the compounds for the identification of 5-HT-3 receptors and the detection and treatment of abnormal conditions associated therewith.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.