Starting materials in the synthesis of thrombin and kinogenase inhibitors

US5723444A · kind A · utility

Assignee

• Astra AB · SE

Inventors

• Karl Thomas Antonsson · Lindome, SE
• Ruth Elvy Bylund · Mölndal, SE
• Nils David Gustafsson · Lindome, SE
• Nils Olov Ingemar Nilsson · Lerum, SE

Key dates

• Filing date: Jun 6, 1995
• Grant date: Mar 3, 1998
• Expiry date: Jun 6, 2015

Classification

• Technology area (CPC Y): Emerging Cross-Sectional Technologies
• CPC primary: Y02P20/55
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The invention concerns the compounds of the formulas: ##STR1## and protected forms and salts thereof which serve as starting materials in an improved method of synthesizing thrombin and kininogenase inhibitors. The invention further concerns an improved method for synthesizing the inhibitors which utilizes the compounds.