Peptide analogs of bombesin

US5723578A · kind A · utility

Assignees

• The Administrators of the Tulane Educational Fund · US
• Biomeasure, Incorporated · US

Inventors

• David H. Coy · New Orleans, US
• Jacques-Pierre Moreau · Upton, US
• Sun H. Kim · Needham, US

Key dates

• Filing date: Jun 7, 1995
• Grant date: Mar 3, 1998
• Expiry date: Jun 7, 2015

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61K38/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Linear peptide analogs of bombesin with modified amino acid residues at various positions. A peptide of a group of bombesin analogs according to this invention contains either a --CH.sub.2 NH.sub.2 -- pseudopeptide bond, a (3S,4S)-4-amino-3-hydroxy- 6-methylheptanoic acid residue, or a (3S,4S)-4-amino-3- hydroxy-5-phenylpentanoic acid residue.