Process for the preparation of pure 4,6-dihloropyrimidine

US5723612A · kind A · utility

Assignee

• DSM Chemie Linz GmbH · AT

Inventors

• Wolfgang Huber · Tittmoning, DE
• Franz Thomas Schwarz · Steyr, AT
• Ferdinand Heu · Linz, AT

Key dates

• Filing date: Jun 3, 1996
• Grant date: Mar 3, 1998
• Expiry date: Jun 3, 2016

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D239/30
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

Process for the preparation of pure 4,6-dichloropyrimidine by reaction of 4,6-dihydroxypyrimidine with an excess of phosphorus oxychloride at 20.degree. C. up to reflux temperature, in the presence of a trialkylamine as acid scavenger and catalyst.