Patent · US Expired

Process for the preparation of a growth hormone secretagogue

US5723616A · kind A · utility

9Cited by
1References
26Claims
0Family size

Assignee

Inventors

Key dates

Filing dateOct 23, 1996
Grant dateMar 3, 1998
Priority date
Expiry dateOct 23, 2016

Classification

  • Technology area (CPC A)Human Necessities
  • CPC primaryA61K38/00
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

The present invention is directed to a novel process for the preparation of the compound N-1(R)-(1,2-dihydro-1-methanesulfonyl-spiro3H-indole-3,4'-piperdin!-1'- yl)carbonyl!-2-(phenylmethyl-oxy)ethyl!-2-amino-2-methyl-propanamide, and salts thereof, which has the structure: ##STR1## and which has the ability to stimulate the release of natural or endogenous growth hormone. This compound may be used to treat conditions which require the stimulation of growth hormone production or secretion such as in humans with a deficiency of natural growth hormone or in animals used for food or wool production where the stimulation of growth hormone will result in a larger, more productive animal.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.