Transgenic plants expressing disassembly deficient viral coat proteins
US5723750A · kind A · utility
Assignees
Inventors
Key dates
| Filing date | Jan 12, 1995 |
| Grant date | Mar 3, 1998 |
| Priority date | — |
| Expiry date | Jan 12, 2015 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2770/00022
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present invention provides a method for protecting plants against infection by pathogenic plant viruses comprising administering to the plant a nucleic acid, encoding a pathogenic plant virus protein, containing substitutions in the genetic sequence which result in the replacement of amino acids having carboxylate side chains with uncharged amino acids and which have the phenotypic effect of displacing wild type coat proteins in a wild type virus and inhibiting the ability of the wild type virus to disassemble under conditions whereby the nucleic acid is expressed as a mutant coat protein within the plant. Also provided is a nucleic acid, encoding a pathogenic plant virus protein, containing substitutions in the genetic sequence which result in the replacement of amino acids having carboxylate side chains with uncharged amino acids and which have the phenotypic effect of displacing wild type coat proteins in a wild type virus and inhibiting the ability of the wild type virus to disassemble.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.