Microcrystalline cellulose spheronization composition
US5725886A · kind A · utility
29Cited by
3References
18Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Sep 26, 1994 |
| Grant date | Mar 10, 1998 |
| Priority date | — |
| Expiry date | Sep 26, 2014 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC08L1/28
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A particulate co-processed unattrited microcrystalline cellulose:hydrocolloid composition wherein the respective components are present in a weight ratio of from about 99:1 to 70:30. The composition is useful as a spheronizing agent for producing spheroids of uniform size and sphericity and having high drug loadings. The composition is produced by drying a slurry of the microcrystalline cellulose in an aqueous solution of the hydrocolloid. The preferred hydrocolloid is methylcellulose.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.