Cosmetic compositions including tropoelastin isomorphs
US5726040A · kind A · utility
Inventors
Key dates
| Filing date | May 2, 1996 |
| Grant date | Mar 10, 1998 |
| Priority date | — |
| Expiry date | May 2, 2016 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K2800/86
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A cosmetic composition including a non naturally-occurring extracellular matrix protein in combination with a cosmetic carrier is described. The protein is preferably of human origin and has not been previously cross-linked. The protein is most preferably selected from the group consisting of soluble human procollagen and soluble human tropoelastin. The protein may include at least one additional non-naturally occurring amino acid sequence moiety, the amino acid sequence moiety selected from the group consisting of a hydrophobic sequence, a hydrophilic sequence, and a lysine-rich sequence. A cosmetic composition in which the non naturally-occurring extracellular matrix protein is an isomorphic form of the protein is also described. The isomorph of the protein is preferably selected from the group consisting of elastin isomorphs, collagen isomorphs and fibronectin isomorphs. Most preferably, the isomorphs are of human origin and have not been previously cross-linked. Methods of making and using a cosmetic composition of the invention are also described.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.