Cytokine regulatory agents and methods of use in pathologies and conditions associated with altered cytokine levels
US5726156A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Sep 12, 1995 |
| Grant date | Mar 10, 1998 |
| Priority date | — |
| Expiry date | Sep 12, 2015 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K38/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to novel peptides that are potent cytokine regulatory agents. In addition, the present invention relates to pharmaceutical compositions comprising a pharmaceutically acceptable carrier and a cytokine regulatory agent. Administration of such a cytokine regulatory agent to a subject can enhance or restrain cytokine activity. Thus, the present invention provides a method of regulating cytokine activity in a subject having a condition characterized by aberrant or altered cytokine activity. The invention also provides methods of treating such conditions, including, for example, disuse deconditioning, diseases mediated by nitric oxide and cytokines, adverse drug reactions, obesity, septic shock, and adverse side effects due to cancer chemotherapy or occurring as in response to organ transplantation.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.