Process for the synthesis of oligonucleotides and analogs with low water oxidation step
US5726300A · kind A · utility
2Cited by
7References
28Claims
0Family size
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Key dates
| Filing date | Jun 15, 1994 |
| Grant date | Mar 10, 1998 |
| Priority date | — |
| Expiry date | Jun 15, 2014 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07H21/00
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Methods of synthesizing oligomers using low water oxidizer reagents which result in high coupling efficiencies are provided. These methods are suitable for larger scale preparations of methylphosphonate oligomers.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.