Certain 3-hydroxy-6-hydroxymethyl-pyridine intermediates
US5726315A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | May 23, 1996 |
| Grant date | Mar 10, 1998 |
| Priority date | — |
| Expiry date | May 23, 2016 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D213/65
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The compounds of the invention are tri-substituted pyridine intermediates, useful in the preparation of final products, wherein said final products are involved in the preparation of medicaments. Said medicaments are useful for the treatment of various diseases including psoriasis. A compound of the formula (II): ##STR1## wherein R.sup.1 is hydrogen, benzyl or a group of the formula (A): ##STR2## in which n is 1 to 20; and R.sup.5 is hydrogen, C.sub.1-6 alkyl, C.sub.1-6 alkoxy or trifluoromethyl; and R.sup.7 is a leaving group consisting of halogen, OTf or (Trifluorate, e.g. OSO.sub.2 CF.sub.3), OSO.sub.2 alkyl and OSO.sub.2 Ar wherein Ar represents optionally substituted aryl.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.